cis-1-[2-[(Acetyloxy)methyl]-1,3-oxathiolan-5-yl]-5-fluoro-2,4(1H,3H)-pyrimidinedione
Product Name |
cis-1-[2-[(Acetyloxy)methyl]-1,3-oxathiolan-5-yl]-5-fluoro-2,4(1H,3H)-pyrimidinedione
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Product Code |
C00005669
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Chemical name |
cis-1-[2-[(Acetyloxy)methyl]-1,3-oxathiolan-5-yl]-5-fluoro-2,4(1H,3H)-pyrimidinedione
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Synonyms |
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Impurity |
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CAS Number |
144963-94-0
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Alternate CAS # |
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Molecular form |
C₁₀H₁₁FN₂O₅S
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Appearance |
Off-White Solid
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Melting Point |
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Mol. Weight |
290.27
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Storage |
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Solubility |
Dimethylsulfoxide, Methanol
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Stability |
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Category |
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Boiling Point |
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Applications |
cis-1-[2-[(Acetyloxy)methyl]-1,3-oxathiolan-5-yl]-5-fluoro-2,4(1H,3H)-pyrimidinedione is an impurity in the synthesis of Labelled Emtricitabine which is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
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Dangerous Goods Info |
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References |
Schinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. Infec. Dis., 182, 599 (2000)
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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