N-(3-Acetyl-4-hydroxyphenyl)acetamide
Product Name |
N-(3-Acetyl-4-hydroxyphenyl)acetamide
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Product Code |
N00001902
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Chemical name |
N-(3-Acetyl-4-hydroxyphenyl)acetamide
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Synonyms |
3’-Acetyl-4’-hydroxyacetanilide; 2-Acetyl-4-acetamidophenol; 2-Acetyl-4-acetylamino-5-nitrophenol; 3-Acetyl-4-hydroxyacetanilide; 5-Acetamido-2-hydroxyacetophenone; 5’-(Acetylamino)-2’-hydroxyacetophenone; 5’-Acetamido-2’-hydroxyacetophenone
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Impurity |
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CAS Number |
7298-67-1
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Alternate CAS # |
NA
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Molecular form |
C₁₀H₁₁NO₃
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Appearance |
Light Yellow Solid
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Melting Point |
166-167°C
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Mol. Weight |
193.2
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Storage |
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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Solubility |
DMSO (Slightly), Methanol (Slightly)
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Stability |
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Category |
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Boiling Point |
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Applications |
N-(3-Acetyl-4-hydroxyphenyl)acetamide is a useful synthetic intermediate in the synthesis of rac Diacetolol (D305200); the principal metabolite of Acebutolol (A123800) with less β-adrenoceptor blocking potency but greater cardioselectivity (atrial relative to tracheal tissue).
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Dangerous Goods Info |
NA
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References |
Basil, B. et al.: Nouv. Pres, Med., 7, 3258 (1978); Choi, S. et al.: Arch. Pharm. Res., 25, 541 (2002); Basil, B. et al.: Eur. J. Pharmacol., 80, 47 (1982)
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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