Product Name | Almorexant |
Product Code | A00003966 |
Chemical name | Almorexant |
Synonyms | (αR,1S)-3,4-Dihydro-6,7-dimethoxy-N-methyl-α-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-2(1H)-isoquinolineacetamide; ACT 078573 |
Impurity | |
CAS Number | 871224-64-5 |
Alternate CAS # | |
Molecular form | C₂₉H₃₁F₃N₂O₃ |
Appearance | |
Melting Point | |
Mol. Weight | 512.56 |
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Applications | Almorexant is a dual orexin receptor antagonist ACT-541468 used in the treatment of insomnia. It regulates sleep and wakefulness through two G protein-coupled receptors, namely Orexin 1 receptor and Orexin 2 receptor. |
Dangerous Goods Info | |
References | Treiber, A., et al.: J. Pharmacol. Exp. Ther., 362, 489 (2017); Beuckmann, C. T., et al.: J. Pharmacol. Exp. Ther.,362, 287 (2017); Tang, L., et al.: Guoji Yaoxue Yanjiu Zazhi, 42, 85 (2015) |
Extra Notes | |
Documents (MSDS) | No Data Available |
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