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Agomelatine
| Product Name | Agomelatine |
| Product Code | A00003148 |
| Chemical name | Agomelatine |
| Synonyms | N-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide; N-[2-(7-Methoxy-1-naphthyl) ethyl]acetamide; S 20098; Valdoxan; |
| Impurity | |
| CAS Number | 138112-76-2 |
| Alternate CAS # | NA |
| Molecular form | C₁₅H₁₇NO₂ |
| Appearance | White to Off-White Solid |
| Melting Point | 106-108°C |
| Mol. Weight | 243.3 |
| Storage | -20°C Freezer |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Stability | |
| Category | Aromatics, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals, |
| Boiling Point | |
| Applications | Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. |
| Dangerous Goods Info | Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g in the package |
| References | Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003), |
| Extra Notes | |
| Documents (MSDS) | Download Document |
| Keywords | Buy 138112-76-2 | Purchase 138112-76-2 | Order 138112-76-2 | 138112-76-2 supplier | 138112-76-2 manufacturer | 138112-76-2 distributor | 138112-76-2 cost |
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