Product Name |
Abiraterone
|
Product Code |
A0000107
|
Chemical name |
Abiraterone
|
Synonyms |
(3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol; CB 7598;
|
Impurity |
|
CAS Number |
154229-19-3
|
Alternate CAS # |
NA
|
Molecular form |
C₂₄H₃₁NO
|
Appearance |
White Solid
|
Melting Point |
223-226°C
|
Mol. Weight |
349.51
|
Storage |
Refrigerator
|
Solubility |
Chloroform (Very Slightly), DMSO (Slightly), Methanol (Slightly)
|
Stability |
|
Category |
Pharmaceuticals, Intermediates & Fine Chemicals, Steroids,
|
Boiling Point |
|
Applications |
Abiraterone is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
|
Dangerous Goods Info |
NA
|
References |
Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005);
|
Extra Notes |
|
Documents (MSDS) |
Download Document
|
Keywords |
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