Product Name |
AR-C155858
|
Product Code |
A00002129
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Chemical name |
AR-C155858
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Synonyms |
(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; 2-[[6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxothieno[2,3-d]pyrimidin-5-yl]carbonyl]-4-isoxazolidinol;(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AR-C 155858
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Impurity |
|
CAS Number |
496791-37-8
|
Alternate CAS # |
NA
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Molecular form |
C₂₁H₂₇N₅O₅S
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Appearance |
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Melting Point |
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Mol. Weight |
461.53
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Storage |
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Solubility |
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Stability |
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Category |
Heterocycles, Inhibitor Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
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Boiling Point |
|
Applications |
AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10.
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Dangerous Goods Info |
NA
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References |
Ovens, M.J., et al.: Biochem. J., 425, 523 (2010);
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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