Product Name |
AMG-232
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Product Code |
A00004238
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Chemical name |
AMG-232
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Synonyms |
2-((3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic Acid;
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Impurity |
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CAS Number |
1352066-68-2
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Alternate CAS # |
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Molecular form |
C₂₈H₃₅Cl₂NO₅S
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Appearance |
White Solid
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Melting Point |
160-164ºC
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Mol. Weight |
568.55
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Storage |
-20°C Freezer
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Solubility |
DMSO (Slightly), Methanol (Slightly)
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Stability |
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Category |
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Boiling Point |
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Applications |
AMG-232 is a potent MDM2-P53 inhibitor for use as an anti-tumor agent.
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Dangerous Goods Info |
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References |
Sun, S. et al.: J Med. Chem., 57, 1454 (2014); Ye, Q. et al.: Xenobiotica, 45, 681 (2015);
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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