Product Name | ABT-199-D10 |
Product Code | A0000162 |
Chemical name | ABT-199-D10 |
Synonyms | Venetoclax-d10 |
Impurity | |
CAS Number | NA |
Alternate CAS # | Unlabelled: 1257044-40-8 |
Molecular form | C₄₅H₄₀D₁₀ClN₇O₇S |
Appearance | |
Melting Point | |
Mol. Weight | 878.5 |
Storage | |
Solubility | |
Stability | |
Category | |
Boiling Point | |
Applications | ABT-199-D10 is a deuterized form of ABT 199 (A112430), which is a potent and selective BCL-2 inhibitor that achieves potent antitumor activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer. |
Dangerous Goods Info | NA |
References | Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013); |
Extra Notes | |
Documents (MSDS) | No Data Available |
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