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A66
| Product Name | A66 |
| Product Code | A000043 |
| Chemical name | A66 |
| Synonyms | (2S)-N1-[2-(1,1-Dimethylethyl)-4’-methyl[4,5’-bithiazol]-2’-yl]-1,2-pyrrolidinedicarboxamide; (2S)-1-N-[5-(2-tert-Butyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide |
| Impurity | |
| CAS Number | 1166227-08-2 |
| Alternate CAS # | NA |
| Molecular form | C₁₇H₂₃N₅O₂S₂ |
| Appearance | |
| Melting Point | |
| Mol. Weight | 393.53 |
| Storage | |
| Solubility | |
| Stability | |
| Category | Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |
| Boiling Point | |
| Applications | A66 is a potent and specific p110α inhibitor. Inhibition of p110α can block phosphoinositide 3-kinase (PI3K) signalling and tumor growth in certain cell types. |
| Dangerous Goods Info | NA |
| References | Jamieson, S., et al.: Biochem. J., 438, 53 (2011); Wang, X., et al.: Acta Pharmacol. Sin., 34, 1201 (2013); Smith, G.C., et al.: FEBS J., 280, 5337 (2013) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 1166227-08-2 | Purchase 1166227-08-2 | Order 1166227-08-2 | 1166227-08-2 supplier | 1166227-08-2 manufacturer | 1166227-08-2 distributor | 1166227-08-2 cost |
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