5-Acetoxy-2-bromo-1,4-naphthoquinone
Product Name |
5-Acetoxy-2-bromo-1,4-naphthoquinone
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Product Code |
A0000951
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Chemical name |
5-Acetoxy-2-bromo-1,4-naphthoquinone
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Synonyms |
2-Bromo-5-acetoxy-1,4-naphthoquinone; 5-Acetoxy-2-bromo-1,4-naphthalenedione
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Impurity |
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CAS Number |
77189-69-6
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Alternate CAS # |
NA
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Molecular form |
C₁₂H₇BrO₄
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Appearance |
Yellow Solid
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Melting Point |
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Mol. Weight |
295.09
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Storage |
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Solubility |
Chloroform, Dichloromethane, Ethyl Acetate, Methanol
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Stability |
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Category |
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Boiling Point |
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Applications |
5-Acetoxy-2-bromo-1,4-naphthoquinone is an intermediate in the synthesis of Plumbagin-d3 (P627002). Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
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Dangerous Goods Info |
NA
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References |
Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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