4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone1
Product Name |
4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone1
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Product Code |
AM00008015
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Chemical name |
4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone
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Synonyms |
Capecitabine Impurity
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Impurity |
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CAS Number |
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Alternate CAS # |
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Molecular form |
C₁₃H₁₆FN₃O₆
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Appearance |
Off-White Solid
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Melting Point |
>194°C (dec.)
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Mol. Weight |
329.28
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Storage |
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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Solubility |
Chloroform (Slightly), Methanol (Slightly)
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Stability |
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Category |
Carbohydrates & Derivatives, Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
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Boiling Point |
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Applications |
4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone is an impurity of Capecitabine (C175650), which is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).
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Dangerous Goods Info |
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References |
Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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