4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine
Product Name |
4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine
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Product Code |
A00007242
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Chemical name |
4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine
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Synonyms |
1-(1,1-Dimethylethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; AGL 1872; PP1;
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Impurity |
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CAS Number |
172889-26-8
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Alternate CAS # |
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Molecular form |
C₁₆H₁₉N₅
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Appearance |
Off-White to Grey Solid
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Melting Point |
205 - 207°C
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Mol. Weight |
281.36
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Storage |
-20°C Freezer
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Solubility |
Chloroform, Ethyl Acetate, Methanol
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Stability |
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Category |
Heterocycles, Nucleotides, Bases & Related Reagent, Protein Kinase Inhibitors and Activators
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Boiling Point |
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Applications |
A highly potent and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase.
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Dangerous Goods Info |
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References |
Alessi, D., et al.: J. Biol. Chem., 270, 27489 (1995), Regan, J., et al.: J. Med. Chem., 45, 2994 (2002), Bain, J., et al.: Biochem. J., 2003, 371, 199 (2003), Bhat, R., et al.: J. Biol. Chem., 278, 45937 (2003), Wilhelm, S., et al.: Cancer Res., 64, 7099 (2004),
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Extra Notes |
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Documents (MSDS) |
Download Document
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Keywords |
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