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4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine

Product Name 4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine
Product Code A00007242
Chemical name 4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine
Synonyms 1-(1,1-Dimethylethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; AGL 1872; PP1;
Impurity
CAS Number 172889-26-8
Alternate CAS #
Molecular form C₁₆H₁₉N₅
Appearance Off-White to Grey Solid
Melting Point 205 - 207°C
Mol. Weight 281.36
Storage -20°C Freezer
Solubility Chloroform, Ethyl Acetate, Methanol
Stability
Category Heterocycles, Nucleotides, Bases & Related Reagent, Protein Kinase Inhibitors and Activators
Boiling Point
Applications A highly potent and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase.
Dangerous Goods Info
References Alessi, D., et al.: J. Biol. Chem., 270, 27489 (1995), Regan, J., et al.: J. Med. Chem., 45, 2994 (2002), Bain, J., et al.: Biochem. J., 2003, 371, 199 (2003), Bhat, R., et al.: J. Biol. Chem., 278, 45937 (2003), Wilhelm, S., et al.: Cancer Res., 64, 7099 (2004),
Extra Notes
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4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine
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