4-Amino-1-tert-butyl-3-(1’-naphthyl)pyrazolo[3,4-d]pyrimidine
Product Name |
4-Amino-1-tert-butyl-3-(1’-naphthyl)pyrazolo[3,4-d]pyrimidine
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Product Code |
A00007254
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Chemical name |
4-Amino-1-tert-butyl-3-(1’-naphthyl)pyrazolo[3,4-d]pyrimidine
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Synonyms |
1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-NA-PP1;
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Impurity |
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CAS Number |
221243-82-9
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Alternate CAS # |
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Molecular form |
C₁₉H₁₉N₅
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Appearance |
White to Off-White Solid
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Melting Point |
215-218°C
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Mol. Weight |
317.39
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Storage |
-20°C Freezer
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Solubility |
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
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Stability |
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Category |
Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
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Boiling Point |
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Applications |
A highly potent (IC50=1.5nM) and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase.
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Dangerous Goods Info |
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References |
Bishop, A.C., et al.: J. Am. Chem. Soc., 121, 627 (1999), Davies, S., et al.: Biochem. J., 351, 95 (2000), Regan, J., et al.: J. Med. Chem., 45, 2994 (2002), Bain, J., et al.: Biochem. J., 371, 199 (2003), Kuma, Y., et al.: J. Biol. Chem., 280, 19472 (2005),
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Extra Notes |
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Documents (MSDS) |
Download Document
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Keywords |
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