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2-Amino-3-benzoyl-5-chloro-α-(propylthio)benzeneacetamide
| Product Name | 2-Amino-3-benzoyl-5-chloro-α-(propylthio)benzeneacetamide |
| Product Code | A00005786 |
| Chemical name | 2-Amino-3-benzoyl-5-chloro-α-(propylthio)benzeneacetamide |
| Synonyms | Nepafenac Impurity; |
| Impurity | |
| CAS Number | 1881270-48-9 |
| Alternate CAS # | |
| Molecular form | C₁₈H₁₉ClN₂O₂S |
| Appearance | |
| Melting Point | |
| Mol. Weight | 362.87 |
| Storage | |
| Solubility | |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | 2-Amino-3-benzoyl-5-chloro-α-(propylthio)benzeneacetamide is derived from Methyl Chloroacetate (M294960), which is widely used in the chemical and biochemical fields as an extraction solvent. Methyl chloroacetate is known to induce DNA damage to rat sperm, and is also thought to be toxic to humans upon exposure. Methyl chloroacetate is also used as a reagent to synthesize Valdecoxib (V090000), a selective cyclooxygenase 2(COX-2) specific inhibitor that is used to treat postoperative pain; Also, it is a non-steroidal anti-inflammatory drug (NSAID). |
| Dangerous Goods Info | |
| References | Nussmeier, N., et al.: New Engl. J. Med., 352, 1081 (2005); Talley, J., et al.: J. Med. Chem., 43, 775 (2000); Wang, T., et al.: J. Chromatogr. A, 1147, 105 (2007); Wenye, L.: J. Anh. Agri. Sci., 35, 2581 (2007); Runje, M., et al.: J. Pharm. Biomed. Anal., 123, 42-52 (2016) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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