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1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile
| Product Name | 1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile |
| Product Code | A00001297 |
| Chemical name | 1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile |
| Synonyms | 1-Acetyl-5-(2-aminopropyl)-2,3-dihydro-1H-Indole-7-carbonitrile |
| Impurity | |
| CAS Number | 175837-01-1 |
| Alternate CAS # | NA |
| Molecular form | C₁₄H₁₇N₃O |
| Appearance | Brown Solid |
| Melting Point | >83ºC (dec.) |
| Mol. Weight | 243.3 |
| Storage | Hygroscopic, Refrigerator, under inert atmosphere |
| Solubility | Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) |
| Stability | |
| Category | Amines, Aromatics, Heterocycles, Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point | |
| Applications | 1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile is an intermediate in the synthesis of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy. |
| Dangerous Goods Info | NA |
| References | Barve, I.J., et. al.: Tetrahedron, 69, 2834 (2013); Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995); Murata, S., et al.: J. Urol., 164, 578 (2000) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 175837-01-1 | Purchase 175837-01-1 | Order 175837-01-1 | 175837-01-1 supplier | 175837-01-1 manufacturer | 175837-01-1 distributor | 175837-01-1 cost |
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