1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one
Product Name |
1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one
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Product Code |
O00002229
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Chemical name |
1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one
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Synonyms |
(5-O-Acetyl-β-D-ribofuranosyl)-Azacytidine;
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Impurity |
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CAS Number |
1174733-90-4
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Alternate CAS # |
NA
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Molecular form |
C₁₀H₁₄N₄O₆
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Appearance |
White Solid
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Melting Point |
>142°C (dec.)
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Mol. Weight |
286.24
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Storage |
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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Solubility |
DMSO (Slightly), Methanol (Slightly)
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Stability |
Moisture sensitive
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Category |
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Boiling Point |
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Applications |
1-(5-O-Acetyl-β-D-ribofuranosyl)-4-amino-1,3,5-triazin-2(1H)-one is an impurity of 5-Azacytidine (A796000), a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase.
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Dangerous Goods Info |
NA
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References |
Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999), Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999), Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999), Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)
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Extra Notes |
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Documents (MSDS) |
Download Document
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Keywords |
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