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1-(2-Amino-5-hydroxyphenyl)propan-1-one
| Product Name | 1-(2-Amino-5-hydroxyphenyl)propan-1-one |
| Product Code | A00008500 |
| Chemical name | 1-(2-Amino-5-hydroxyphenyl)propan-1-one |
| Synonyms | 2’-Amino-5’-hydroxypropiophenone; AHPP |
| Impurity | |
| CAS Number | 35364-15-9 |
| Alternate CAS # | |
| Molecular form | C₉H₁₁NO₂ |
| Appearance | Brownish Yellow Solid |
| Melting Point | >138°C (dec.) |
| Mol. Weight | 165.19 |
| Storage | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| Solubility | Chloroform, Methanol |
| Stability | |
| Category | Amines, Aromatics, Miscellaneous Reagents |
| Boiling Point | |
| Applications | 1-(2-Amino-5-hydroxyphenyl)propan-1-one is a useful synthetic intermediate. It is used in the asymmetrical synthesis of (S)-4-ethyl-6,7,8,10- tetrahydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, a key intermediate for synthesis of irinotecan and other camptothecin analogs. It is also used in the synthesis of E-ring-modified (RS)-camptothecin analogs as antitumor agents. |
| Dangerous Goods Info | |
| References | Henegar, K., et al.: J. Org. Chem., 62, 6588 (1997); Ejima, A., et al.: Chem. Pharma. Bull., 40, 683 (1992) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 35364-15-9 | Purchase 35364-15-9 | Order 35364-15-9 | 35364-15-9 supplier | 35364-15-9 manufacturer | 35364-15-9 distributor | 35364-15-9 cost |
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