(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one
Product Name |
(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one
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Product Code |
R00001938
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Chemical name |
(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one
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Synonyms |
(R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one;
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Impurity |
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CAS Number |
512177-83-2
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Alternate CAS # |
NA
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Molecular form |
C₁₈H₁₉ClFNO₃
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Appearance |
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Melting Point |
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Mol. Weight |
351.8
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Storage |
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Solubility |
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Stability |
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Category |
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Boiling Point |
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Applications |
(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one, is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM.
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Dangerous Goods Info |
NA
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References |
Zweemer AJ, et al.: Mol Pharmacol. 2013 Oct;84(4):551-61.;
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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