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(±)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methyl-piperidine
| Product Name | (±)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methyl-piperidine |
| Product Code | A00005049 |
| Chemical name | (±)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methyl-piperidine |
| Synonyms | 3-(3,4-dimethoxyphenyl)-1-methyl-4-piperidinamine |
| Impurity | |
| CAS Number | 24218-09-5 |
| Alternate CAS # | |
| Molecular form | C₁₄H₂₂N₂O₂ |
| Appearance | Semi-Solid (Brown) |
| Melting Point | |
| Mol. Weight | 250.34 |
| Storage | |
| Solubility | Dichloromethane, Ether, Ethyl Acetate, Methanol |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | (±)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methyl-piperidine is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension. |
| Dangerous Goods Info | |
| References | Huxtable, R., et al.: Pharmacol. Ther., 47, 371 (1990), Tanaka, K., et al.: Cancer Res., 55, 2927 (1995), Wagner, R., et al.: J. Pharmacol. Exp. Ther., 282, 1650 (1997), Cowan, K., et al.: Nat. Med., 6, 698 (2000), Shankavaram, U., et al.: J. Biol. Chem., 276, 19027 (2001), |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 24218-09-5 | Purchase 24218-09-5 | Order 24218-09-5 | 24218-09-5 supplier | 24218-09-5 manufacturer | 24218-09-5 distributor | 24218-09-5 cost |
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