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3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide

Product Name 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide
Product Code A00008519
Chemical name 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide
Synonyms USP Famotidine Related Compound C; Famotidine EP Impurity D
Impurity Famotidine EP Impurity D
CAS Number 76824-16-3
Alternate CAS #
Molecular form C₈H₁₃N₅OS₂
Appearance Off-White to Pale Yellow Solid
Melting Point >140ºC (dec.)
Mol. Weight 259.35
Storage Hygroscopic, Refrigerator, under inert atmosphere
Solubility DMSO (Slightly), Methanol (Slightly)
Stability
Category Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point
Applications 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide is an impurity in the synthesis of Famotidine (F102250) histamine H2-receptor antagonist. Antiulcerative.
Dangerous Goods Info
References Takeda, M., et al.: Arzneim.-Forsch., 32, 734 (1982), Miwa, M., et al.: J. Clin. Pharmacol. Ther. Toxicol., 22, 214 (1984), Takabatke, T., et al.: Eur. J. Clin. Pharmacol., 28, 327 (1985),
Extra Notes
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3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide
Product Packings
5mg
25mg
100mg
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