3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide
Product Name |
3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide
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Product Code |
A00008519
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Chemical name |
3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide
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Synonyms |
USP Famotidine Related Compound C; Famotidine EP Impurity D
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Impurity |
Famotidine EP Impurity D
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CAS Number |
76824-16-3
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Alternate CAS # |
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Molecular form |
C₈H₁₃N₅OS₂
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Appearance |
Off-White to Pale Yellow Solid
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Melting Point |
>140ºC (dec.)
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Mol. Weight |
259.35
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Storage |
Hygroscopic, Refrigerator, under inert atmosphere
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Solubility |
DMSO (Slightly), Methanol (Slightly)
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Stability |
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Category |
Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
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Boiling Point |
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Applications |
3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide is an impurity in the synthesis of Famotidine (F102250) histamine H2-receptor antagonist. Antiulcerative.
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Dangerous Goods Info |
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References |
Takeda, M., et al.: Arzneim.-Forsch., 32, 734 (1982), Miwa, M., et al.: J. Clin. Pharmacol. Ther. Toxicol., 22, 214 (1984), Takabatke, T., et al.: Eur. J. Clin. Pharmacol., 28, 327 (1985),
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Extra Notes |
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Documents (MSDS) |
Download Document
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Keywords |
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