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4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone1

Product Name 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone1
Product Code AM00008015
Chemical name 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone
Synonyms Capecitabine Impurity
Impurity
CAS Number
Alternate CAS #
Molecular form C₁₃H₁₆FN₃O₆
Appearance Off-White Solid
Melting Point >194°C (dec.)
Mol. Weight 329.28
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility Chloroform (Slightly), Methanol (Slightly)
Stability
Category Carbohydrates & Derivatives, Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point
Applications 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone is an impurity of Capecitabine (C175650), which is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).
Dangerous Goods Info
References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),
Extra Notes
Documents (MSDS) No Data Available
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4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone1
Product Packings
10mg
100mg
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