(R)-2-Amino-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanol
Product Name |
(R)-2-Amino-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanol
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Product Code |
R00007944
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Chemical name |
(R)-2-Amino-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanol
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Synonyms |
(1R)-2-Amino-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanol; (αR)-α-(aminomethyl)-2,2-dimethyl-4H-1,3-benzodioxin-6-methanol
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Impurity |
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CAS Number |
208925-08-0
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Alternate CAS # |
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Molecular form |
C₁₂H₁₇NO₃
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Appearance |
Solid
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Melting Point |
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Mol. Weight |
223.27
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Storage |
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Solubility |
Dichloromethane, Ethyl Acetate, Methanol
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Stability |
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Category |
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Boiling Point |
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Applications |
(1R)-2-Amino-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanol is an intermediate in the synthesis of Vilanterol Trifenatate-d4 (V260002). Vilanterol Trifenatate (V260000) is a long-acting β2 adrenergic receptor Agonist. It demonstrates prolonged bronchodilation in subjects with asthma and COPD.
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Dangerous Goods Info |
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References |
Procopiou, P., et al.: J. Med. Chem., 53, 4522 (2010); Kempsford, R., et al.: Pulm. Pharmacol. Ther., 26,
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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