(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one
Product Name |
(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one
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Product Code |
S00007732
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Chemical name |
(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one
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Synonyms |
(7S)-7-Amino-5,7-dihydro-6H-dibenz[b,d]azepin-6-one;
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Impurity |
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CAS Number |
847926-88-9
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Alternate CAS # |
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Molecular form |
C₁₄H₁₂N₂O
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Appearance |
White Solid
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Melting Point |
218-221°C dec.
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Mol. Weight |
224.26
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Storage |
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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Solubility |
Chloroform (Slightly), Methanol (Slightly)
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Stability |
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Category |
Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
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Boiling Point |
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Applications |
(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one a building block for γ-secretase inhibitors for treatment of Alzheimer’s disease (1,2). Several γ-secretase inhibitors have been described that contain this compound.
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Dangerous Goods Info |
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References |
(1) Beher, D., et al.: Exp. Opin. Investig. Drugs, 14, 1385 (2005)
(2) Fauq, A., et al.: Bioorg. Med. Chem. Lett., 17, 6392 (2007)
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Extra Notes |
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Documents (MSDS) |
Download Document
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Keywords |
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