6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile
Product Name |
6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile
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Product Code |
A00007598
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Chemical name |
6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile
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Synonyms |
4-[4-[(2-Pyridyl)methoxy]-3-chloroanilino]-6-amino-3-cyano-7-ethoxyquinoline; 6-Amino-4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxyquinoline
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Impurity |
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CAS Number |
848139-69-6
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Alternate CAS # |
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Molecular form |
C₂₄H₂₀ClN₅O₂
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Appearance |
Off-White to Pale Yellow Solid
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Melting Point |
236-238°C (dec.)
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Mol. Weight |
445.9
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Storage |
Refrigerator
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Solubility |
Dichlomethane (Slightly), DMSO (Slightly)
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Stability |
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Category |
Aromatic, Heterocycles, Amines, Pharmaceuticals, Intermediates & Fine Chemicals
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Boiling Point |
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Applications |
6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile, is used in the synthetic preparation of aminopropanamides which is used in irreversible inhibition of epidermal growth factor receptor (EGFR) for potential use in cancer therapy.
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Dangerous Goods Info |
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References |
Carmi, C., et al.: J. Med. Chem., 55, 2251 (2012)
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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