N-[4-Amino-2-chloro-6-[(2-deoxy-2-fluoro-β-D-arabinopyranosyl)amino]-5-pyrimidinyl]-formamide
Product Name |
N-[4-Amino-2-chloro-6-[(2-deoxy-2-fluoro-β-D-arabinopyranosyl)amino]-5-pyrimidinyl]-formamide
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Product Code |
N00006902
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Chemical name |
N-[4-Amino-2-chloro-6-[(2-deoxy-2-fluoro-β-D-arabinopyranosyl)amino]-5-pyrimidinyl]-formamide
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Synonyms |
N-(4-Amino-2-chloro-6-(((2R,3S,4R,5R)-3-fluoro-4,5-dihydroxytetrahydro-2H-pyran-2-yl)amino)pyrimidin-5-yl)formamide
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Impurity |
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CAS Number |
1140251-33-7
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Alternate CAS # |
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Molecular form |
C₁₀H₁₃ClFN₅O₄
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Appearance |
White Solid
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Melting Point |
>172°C (dec.)
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Mol. Weight |
321.69
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Storage |
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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Solubility |
DMSO (Slightly), Methanol (Slightly)
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Stability |
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Category |
Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
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Boiling Point |
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Applications |
N-[4-Amino-2-chloro-6-[(2-deoxy-2-fluoro-β-D-arabinopyranosyl)amino]-5-pyrimidinyl]-formamide is a clofarabine related compound. Clofarabine (C586890) is a second generation purine nucleoside analog; antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic.
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Dangerous Goods Info |
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References |
Gandhi, V., et al.: Clin. Cancer Res., 9, 6335 (2003), Kantarjian, H., et al.: Blood, 102, 2379 (2003), Faderl, S., et al.: Cancer, 103, 1985 (2005),
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Extra Notes |
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Documents (MSDS) |
Download Document
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Keywords |
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