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trans-4-Acetamidocyclohexanol
| Product Name | trans-4-Acetamidocyclohexanol |
| Product Code | T0000520 |
| Chemical name | trans-4-Acetamidocyclohexanol |
| Synonyms | trans-N-(4-Hydroxycyclohexyl)-acetamide; trans-N-Acetyl-4-hydroxycyclohexylamine |
| Impurity | |
| CAS Number | 27489-60-7 |
| Alternate CAS # | NA |
| Molecular form | C₈H₁₅NO₂ |
| Appearance | |
| Melting Point | |
| Mol. Weight | 157.21 |
| Storage | |
| Solubility | |
| Stability | |
| Category | Amines, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point | |
| Applications | trans-4-Acetamidocyclohexanol is an intermediate in the synthesis of 4”-trans-Hydroxy Cilostazol (H918300), a metabolite of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo. |
| Dangerous Goods Info | NA |
| References | de Morais, S., et al.: J. Biol. Chem., 269, 15419 (1994); Tata, P; J Pharm Biomed Anal, 24, 381, (2001); Hiratsuka, M; Eur J Clin Pharmacol, 58, 417 (2002); Roy, J; Drug Metab Dispos, 33, 884 (2005); Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998); Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999); Tsuchikane, E., et al.: Circulation, 100, 21 (1999) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 27489-60-7 | Purchase 27489-60-7 | Order 27489-60-7 | 27489-60-7 supplier | 27489-60-7 manufacturer | 27489-60-7 distributor | 27489-60-7 cost |
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