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2-Amino-N-(2,4-dichloro-6-methylphenyl)thiazole-5-carboxamide

Product Name 2-Amino-N-(2,4-dichloro-6-methylphenyl)thiazole-5-carboxamide
Product Code A00005121
Chemical name 2-Amino-N-(2,4-dichloro-6-methylphenyl)thiazole-5-carboxamide
Synonyms Dasatinib Impurity
Impurity
CAS Number
Alternate CAS #
Molecular form C₁₁H₉Cl₂N₃OS
Appearance
Melting Point
Mol. Weight 302.18
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Applications 2-Amino-N-(2,4-dichloro-6-methylphenyl)thiazole-5-carboxamide is an impurity of the anti-cancer drug Dasatinib (D193600). Dasatinib is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic.
Dangerous Goods Info
References Lombardo, L.J., et al: J. Med. Chem., 47, 6658 (2004); Shah, N. P., et al.: Science, 305, 399 (2004); O’Hare, T., et al.: Curr. Opin. Genet. Dev., 16, 92 (2006)
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2-Amino-N-(2,4-dichloro-6-methylphenyl)thiazole-5-carboxamide
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