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Ambrisentan-d10

Product Name Ambrisentan-d10
Product Code A00004078
Chemical name Ambrisentan-d10
Synonyms (αS)-α-[(4,6-dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-(phenyl-2,3,4,5,6-d5)benzene-2,3,4,5,6-d5-propanoic Acid; BSF 208075-d10; LU 208075-d10;
Impurity
CAS Number 1046116-27-1
Alternate CAS # Unlabelled: 177036-94-1
Molecular form C₂₂H₁₂D₁₀N₂O₄
Appearance White to Off-White Solid
Melting Point >160°C (dec.)
Mol. Weight 388.48
Storage -20°C Freezer
Solubility DMSO (Slightly), Methanol (Slightly)
Stability
Category Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point
Applications Ambrisentan-d10, is the labeled analogue of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.
Dangerous Goods Info
References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),
Extra Notes
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Ambrisentan-d10
Product Packings
1mg
10mg
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