Product Name |
Alvimopan
|
Product Code |
A00004052
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Chemical name |
Alvimopan
|
Synonyms |
N-[(2S)-2-[[(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]glycine; ADL 8-2698; LY 246736; Entereg;
|
Impurity |
|
CAS Number |
156053-89-3
|
Alternate CAS # |
Monohydrate: 1383577-62-5
|
Molecular form |
C₂₅H₃₂N₂O₄
|
Appearance |
White Solid
|
Melting Point |
200 - 204°C
|
Mol. Weight |
424.53
|
Storage |
Refrigerator
|
Solubility |
DMSO (Slightly), Methanol (Slightly, Sonicated, Heated)
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Stability |
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Category |
Amines, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
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Boiling Point |
|
Applications |
A peripheral µ-opioid receptor antagonist. Gastroprokinetic.
|
Dangerous Goods Info |
|
References |
Zimmerman, D.M., et al.: J. Med. Chem., 37, 2262 (1994), Liu, S.S., et al.: Clin. Pharmacol. Ther., 68, 66 (2000), Taguchi, A., et al.: N. Engl. J. Med., 345, 935 (2001),
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Extra Notes |
|
Documents (MSDS) |
No Data Available
|
Keywords |
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