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Almorexant

Product Name Almorexant
Product Code A00003966
Chemical name Almorexant
Synonyms (αR,1S)-3,4-Dihydro-6,7-dimethoxy-N-methyl-α-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-2(1H)-isoquinolineacetamide; ACT 078573
Impurity
CAS Number 871224-64-5
Alternate CAS #
Molecular form C₂₉H₃₁F₃N₂O₃
Appearance
Melting Point
Mol. Weight 512.56
Storage
Solubility
Stability
Category
Boiling Point
Applications Almorexant is a dual orexin receptor antagonist ACT-541468 used in the treatment of insomnia. It regulates sleep and wakefulness through two G protein-coupled receptors, namely Orexin 1 receptor and Orexin 2 receptor.
Dangerous Goods Info
References Treiber, A., et al.: J. Pharmacol. Exp. Ther., 362, 489 (2017); Beuckmann, C. T., et al.: J. Pharmacol. Exp. Ther.,362, 287 (2017); Tang, L., et al.: Guoji Yaoxue Yanjiu Zazhi, 42, 85 (2015)
Extra Notes
Documents (MSDS) No Data Available
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Almorexant
Product Packings
1mg
5mg
10mg
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