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2-Allyl-2,10-didemethyl-colchicine

Product Name 2-Allyl-2,10-didemethyl-colchicine
Product Code A00003765
Chemical name 2-Allyl-2,10-didemethyl-colchicine
Synonyms (S)-N-(3-(Allyloxy)-10-hydroxy-1,2-dimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide;
Impurity
CAS Number
Alternate CAS #
Molecular form C₂₃H₂₅NO₆
Appearance
Melting Point
Mol. Weight 411.45
Storage
Solubility Dichloromethane, Methanol
Stability
Category
Boiling Point
Applications 2-Allyl-2,10-didemethyl-colchicine is an intermediate in synthesizing Isothiocolcicoside (I902755), which is an impurity of Thiocolchicoside (T344385), a GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects.
Dangerous Goods Info
References Gelmi, M., et al.: J. Med. Chem., 50, 2245 (2007); Mascia, M., et al.: Eur. J. Pharmacol., 558, 37 (2007); Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010);
Extra Notes
Documents (MSDS) No Data Available
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2-Allyl-2,10-didemethyl-colchicine
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