Product Name |
A-385358
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Product Code |
A000037
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Chemical name |
A-385358
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Synonyms |
4-[[(R)-3-Dimethylamino-1-[(phenylsulfanyl)methyl]propyl]amino]-N-[4-(4,4-dimethylpiperidin-1-yl)benzoyl]-3-nitrobenzenesulfonamide
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Impurity |
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CAS Number |
406228-55-5
|
Alternate CAS # |
NA
|
Molecular form |
C₃₂H₄₁N₅O₅S₂
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Appearance |
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Melting Point |
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Mol. Weight |
639.83
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Storage |
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Solubility |
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Stability |
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Category |
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Boiling Point |
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Applications |
A-385358, is a selective inhibitor of Bcl-XL with Kis, in vitro. In vivo, A-385358, in combination with the lower dose of paclitaxel produces a significant reduction in tumor growth (%T/C) compare with paclitaxel monotherapy.
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Dangerous Goods Info |
NA
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References |
Shoemaker, A. R. et al.: Cancer Res. 2006 Sep 1;66(17):8731-9;
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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