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4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone
| Product Name | 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone |
| Product Code | A00003631 |
| Chemical name | 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone |
| Synonyms | Capecitabine Impurity |
| Impurity | |
| CAS Number | |
| Alternate CAS # | |
| Molecular form | C₁₃H₁₆FN₃O₆ |
| Appearance | Off-White Solid |
| Melting Point | >194ºC(dec.) |
| Mol. Weight | 329.28 |
| Storage | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Stability | |
| Category | Chloroform (Slightly), Methanol (Slightly) |
| Boiling Point | |
| Applications | 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone is an impurity of Capecitabine (C175650), which is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750). |
| Dangerous Goods Info | |
| References | Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009), |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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