Product Name |
Agomelatine-d6
|
Product Code |
A00003150
|
Chemical name |
Agomelatine-d6
|
Synonyms |
N-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide-d6; N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide-d6; S 20098-d6; Valdoxan-d6
|
Impurity |
No Data Available
|
CAS Number |
1079389-42-6
|
Alternate CAS # |
138112-76-2 unlabelled
|
Molecular form |
C₁₅H₁₁D₆NO₂
|
Appearance |
No Data Available
|
Melting Point |
No Data Available
|
Mol. Weight |
249.34
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Storage |
No Data Available
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Solubility |
No Data Available
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Stability |
No Data Available
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Category |
Amines, Aromatics, Isotope Labelled Compounds, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
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Boiling Point |
No Data Available
|
Applications |
Agomelatine-d6 is labelled Agomelatine (A430000) which is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively.
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Dangerous Goods Info |
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g in the package
|
References |
Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003)
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Extra Notes |
No Data Available
|
Documents (MSDS) |
No Data Available
|
Keywords |
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