Product Name |
ACY-775
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Product Code |
A00003062
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Chemical name |
ACY-775
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Synonyms |
2-[[1-(3-Fluorophenyl)cyclohexyl]amino]-N-hydroxy-5-pyrimidinecarboxamide; 2-((1-(3-Fluorophenyl)cyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide;
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Impurity |
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CAS Number |
1375466-18-4
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Alternate CAS # |
NA
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Molecular form |
C₁₇H₁₉FN₄O₂
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Appearance |
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Melting Point |
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Mol. Weight |
330.36
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Storage |
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Solubility |
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Stability |
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Category |
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Boiling Point |
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Applications |
ACY-775 is a novel histone deacetylase 6-selective (HDAC6) inhibitor with antidepressant and pro-cognitive properties. ACY-775 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.
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Dangerous Goods Info |
NA
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References |
Jochems, J., et al.: Neuropsychopharmacology, 39, 389 (2014)
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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