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AdipoRon

Product Name AdipoRon
Product Code A00003026
Chemical name AdipoRon
Synonyms 2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide; 2-(4-Benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide
Impurity
CAS Number 924416-43-3
Alternate CAS # NA
Molecular form C₂₇H₂₈N₂O₃
Appearance White to Off-White Solid
Melting Point 106-108°C
Mol. Weight 428.52
Storage Refrigerator
Solubility Chloroform (Slightly), Methanol (Slightly)
Stability
Category Agonist, Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point
Applications AdipoRon is an AdipoR agonist and activates AMPK and PPAR-α pathways in the muscle and liver. AdipoRon ameliorated diabetes of genetically obese rodent model db/db mice, and prolonged the shortened lifespan of db/db mice on a high-fat diet. AdipoRon is a promising therapeutic approach for the treatment of obesity-related diseases such as type 2 diabetes.
Dangerous Goods Info NA
References Okada-Iwabu, M., et. al.: Nature, 503, 493 (2013)
Extra Notes
Documents (MSDS) No Data Available
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AdipoRon
Product Packings
5mg
10mg
25mg
50mg
250mg
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