Product Name |
Adefovir
|
Product Code |
A00002916
|
Chemical name |
Adefovir
|
Synonyms |
P-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic Acid; 9-(2-Phosphonylmethoxyethyl)adenine; [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosponic Acid; GS 0393; PMEA;
|
Impurity |
|
CAS Number |
106941-25-7
|
Alternate CAS # |
NA
|
Molecular form |
C₈H₁₂N₅O₄P
|
Appearance |
White to Light Brown Solid
|
Melting Point |
>282°C (dec.)
|
Mol. Weight |
273.19
|
Storage |
-20°C Freezer
|
Solubility |
Methanol (Slightly), Water (Slightly, Heated)
|
Stability |
|
Category |
Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
|
Boiling Point |
|
Applications |
Adefovir is a more toxic analog of Tenofovir. Also, it is used with entecavir as similar efficacy in treating chronic hepatitis B.
|
Dangerous Goods Info |
NA
|
References |
Zhao, X., et al.: Sci. Rep., 7, 46344 (2017); Huang, J., et al.: Zhongguo Yaoye, 25, 29-31 (2016)
|
Extra Notes |
|
Documents (MSDS) |
Download Document
|
Keywords |
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