2-(Adamantan-1-yl)-4-bromophenol
Product Name |
2-(Adamantan-1-yl)-4-bromophenol
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Product Code |
A00002882
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Chemical name |
2-(Adamantan-1-yl)-4-bromophenol
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Synonyms |
2-(1-Adamantyl)-4-bromophenol; 4-Bromo-2-(1-adamantyl)phenol; 2-((3r,5r,7r)-Adamantan-1-yl)-4-bromophenol
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Impurity |
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CAS Number |
104224-68-2
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Alternate CAS # |
NA
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Molecular form |
C₁₆H₁₉BrO
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Appearance |
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Melting Point |
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Mol. Weight |
307.23
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Storage |
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Solubility |
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Stability |
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Category |
Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
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Boiling Point |
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Applications |
2-(Adamantan-1-yl)-4-bromophenol is an intermediate in the synthesis of Adapalene (A225000), a retinoid selective for retinoic acid receptor (RAR) subtypes β and γ; an antiacne agent.
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Dangerous Goods Info |
NA
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References |
Sokolenko, V.A., et. al.: Pharmaceut. Chem. J., 47, 217 (2013); Griffiths, C.E.M., et al.: J. Invest. Dermatol., 101, 325 (1993); Bernard, B.A., et al.: Skin Pharmacol., 6, 61 (1993); Waugh, J., et al.: Drugs, 64, 1465 (2004)
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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