(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide
Product Name |
(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide
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Product Code |
R00002645
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Chemical name |
(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide
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Synonyms |
PF-06465469-00;
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Impurity |
|
CAS Number |
1407966-77-1
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Alternate CAS # |
NA
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Molecular form |
C₃₀H₃₃N₇O₂
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Appearance |
Beige Solid
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Melting Point |
209-212°C
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Mol. Weight |
523.63
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Storage |
Refrigerator
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Solubility |
DMSO (Sparingly), Methanol (Sparingly)
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Stability |
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Category |
Aromatics, Heterocycles, Inhibitors, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
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Boiling Point |
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Applications |
(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide is a potential covalent inhibitor of Interleukin-2 Inducible T Cell KInase (Itk). Itk is a member of the TEC-kinase family and is associated with the induction of T cell proliferation and drives cytokines through NFATc.
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Dangerous Goods Info |
NA
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References |
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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