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Aconitine
| Product Name | Aconitine |
| Product Code | A00002529 |
| Chemical name | Aconitine |
| Synonyms | (1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-Acetate 14-Benzoate; |
| Impurity | |
| CAS Number | 302-27-2 |
| Alternate CAS # | NA |
| Molecular form | C₃₄H₄₇NO₁₁ |
| Appearance | Off-White Solid |
| Melting Point | >180ºC (dec.) |
| Mol. Weight | 645.74 |
| Storage | Refrigerator |
| Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly, Sonicated) |
| Stability | |
| Category | Amines, Aromatics, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point | |
| Applications | Neurotoxin. Activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction. Aconitine also blocks norepinephrine reuptake. In the heart, aconitine induces ventricular tachycardia after intracoronary injection. In cultured ventricular myocytes, aconitine increases the duration of the action potential and induces the appearance of early after depolarization. Used in producing heart arrhythmia in experimental animals. |
| Dangerous Goods Info | Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g in the package |
| References | Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010), Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010), |
| Extra Notes | |
| Documents (MSDS) | Download Document |
| Keywords | Buy 302-27-2 | Purchase 302-27-2 | Order 302-27-2 | 302-27-2 supplier | 302-27-2 manufacturer | 302-27-2 distributor | 302-27-2 cost |
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