Product Name |
ACHP
|
Product Code |
A00002506
|
Chemical name |
ACHP
|
Synonyms |
2-Amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile
|
Impurity |
|
CAS Number |
406208-42-2
|
Alternate CAS # |
NA
|
Molecular form |
C₂₁H₂₄N₄O₂
|
Appearance |
|
Melting Point |
|
Mol. Weight |
364.44
|
Storage |
|
Solubility |
|
Stability |
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Category |
|
Boiling Point |
|
Applications |
ACHP is an IkB kinase inhibitor, which has dose-dependently inhibited cell growth with inhibition of phosphorylation of IκBα/p65 and NF-κB DNA-binding, down-regulation of NF-κB target genes and induced apoptosis in human myeloma cell lines.
|
Dangerous Goods Info |
NA
|
References |
Sanda, T.; et al.: Clin. Cancer Res., 11, 1974 (2005)
|
Extra Notes |
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Documents (MSDS) |
No Data Available
|
Keywords |
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