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5-[2-(Acetyloxy)ethyl]-3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-2(3H)-thiazolethione

Product Name 5-[2-(Acetyloxy)ethyl]-3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-2(3H)-thiazolethione
Product Code A00001983
Chemical name 5-[2-(Acetyloxy)ethyl]-3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-2(3H)-thiazolethione
Synonyms [(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-4-thiazoline-2-thione Acetate; 2-(3-((4-Amino-2-methylpyrimidin-5-yl)methyl)-4-methyl-2-thioxo-2,3-dihydrothiazol-5-yl)ethyl acetate
Impurity
CAS Number 92325-11-6
Alternate CAS # NA
Molecular form C₁₄H₁₈N₄O₂S₂
Appearance White Solid
Melting Point
Mol. Weight 338.45
Storage -20°C Freezer
Solubility Dichloromethane, DMSO, Methanol
Stability
Category
Boiling Point
Applications 5-[2-(Acetyloxy)ethyl]-3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-2(3H)-thiazolethione is an intermediate in synthesizing Thiothiamine (T375250), an impurity of Thiamine (T344185). Thiothiamine inhibits the activity of glutamate decarboxylase and decreases the concentration of GABA in brain tissue. Thiamine Impurity A.
Dangerous Goods Info NA
References Koval’chuk, V.G. et al.: Tezisy Dokl.- Konf. Beloruss. Biokhim. O-va., 2, 135 (1974); Ostrovskii, Y. et al.: Biokhimiya, 34, 488 (1969)
Extra Notes
Documents (MSDS) No Data Available
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5-[2-(Acetyloxy)ethyl]-3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-2(3H)-thiazolethione
Product Packings
50mg
100mg
250mg
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