Product Name |
N-Acetyldesloratadine
|
Product Code |
N00001346
|
Chemical name |
N-Acetyldesloratadine
|
Synonyms |
1-[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-ethanone; 1-Acetyl-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine;
|
Impurity |
|
CAS Number |
117796-52-8
|
Alternate CAS # |
NA
|
Molecular form |
C₂₁H₂₁ClN₂O
|
Appearance |
Off-White to Pale Pink Solid
|
Melting Point |
>61°C (dec.)
|
Mol. Weight |
352.86
|
Storage |
Refrigerator
|
Solubility |
Chloroform (Slightly), Ethyl Acetate (Slightly)
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Stability |
|
Category |
Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
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Boiling Point |
|
Applications |
N-Acetyldesloratadine is an impurity in the synthesis of Desloratadine (D290250), Nonsedating-type histamine H1-receptor antagonist.
|
Dangerous Goods Info |
NA
|
References |
Kreutner, W., et al.: Arzneimittel-Forsch., 50, 345 (2000); Salmun, L.M., et al.: Clin. Ther., 22, 613 (2000); Agrawal, D.K., et al.: Expert Opin. Invest. Drugs, 10, 547 (2001);
|
Extra Notes |
|
Documents (MSDS) |
Download Document
|
Keywords |
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