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3,5-cyclo-Abiraterone

Product Name 3,5-cyclo-Abiraterone
Product Code A0000126
Chemical name 3,5-cyclo-Abiraterone
Synonyms
Impurity
CAS Number NA
Alternate CAS # NA
Molecular form C₂₄H₃₁NO
Appearance White Solid
Melting Point 149-153°C
Mol. Weight 349.51
Storage Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility Chloroform (Slightly), DMSO (Slightly)
Stability
Category
Boiling Point
Applications 3,5-cyclo-Abiraterone is derived from Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
Dangerous Goods Info NA
References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005);
Extra Notes
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3,5-cyclo-Abiraterone
Product Packings
1mg
2.5mg
5mg
10mg
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