Product Name |
Abiaterone-5,6-epoxide
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Product Code |
A0000122
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Chemical name |
Abiaterone-5,6-epoxide
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Synonyms |
5,6-Epoxy Abiaterone
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Impurity |
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CAS Number |
NA
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Alternate CAS # |
NA
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Molecular form |
C₂₄H₃₃NO₂
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Appearance |
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Melting Point |
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Mol. Weight |
367.52
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Storage |
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Solubility |
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Stability |
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Category |
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Boiling Point |
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Applications |
Abiaterone-5,6-Epoxide is an impurity of Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
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Dangerous Goods Info |
NA
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References |
Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)
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Extra Notes |
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Documents (MSDS) |
No Data Available
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Keywords |
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